Science, Tech, Math › Science Common Household Chemicals That Are Dangerous Mixtures A Handy 'Do Not Mix' List Share Flipboard Email Print Floortje / Getty Images Science Chemistry Chemistry In Everyday Life Basics Chemical Laws Molecules Periodic Table Projects & Experiments Scientific Method Biochemistry Physical Chemistry Medical Chemistry Famous Chemists Activities for Kids Abbreviations & Acronyms Biology Physics Geology Astronomy Weather & Climate By Anne Marie Helmenstine, Ph.D. Chemistry Expert Ph.D., Biomedical Sciences, University of Tennessee at Knoxville B.A., Physics and Mathematics, Hastings College Dr. Helmenstine holds a Ph.D. in biomedical sciences and is a science writer, educator, and consultant. She has taught science courses at the high school, college, and graduate levels. our editorial process Facebook Facebook Twitter Twitter Anne Marie Helmenstine, Ph.D. Updated August 12, 2018 Some of the common chemicals found in your home shouldn't be mixed together. It's one thing to say "don't mix bleach with ammonia," but it's not always easy to know what products contain these two chemicals. Here are some household products you may have around the home that shouldn't be combined. Bleach With Acid Toilet Bowl Cleaners This mixture can result in toxic, potentially deadly fumes. Bleach With Vinegar Vinegar is a type of acid. Toxic chlorine vapor is produced. Don't mix chlorine bleach with any acid. Bleach With Ammonia This is toxic. Potentially lethal vapors are produced. The main danger comes from chloramine vapors. Different Brands of One Type of Product Don't mix different cleaners together. They may react violently, produce toxins, or become ineffective. Highly Alkaline Products With Highly Acidic Products Acids and bases (alkalis) can react violently, presenting a splash hazard. Acids and bases are caustic and may cause chemical burns. Certain Disinfectants With Detergents Don't mix disinfectants with 'quaternary ammonia' listed as an ingredient with a detergent. The effectiveness of the disinfectant may be neutralized. Bottom Line Chlorine bleach is sometimes called “sodium hypochlorite” or “hypochlorite.” You will encounter it in chlorine bleach, automatic dishwashing detergents, chlorinated disinfectants and cleaners, chlorinated scouring powder, mildew removers, and toilet bowl cleaners. Do not mix products together. Do not mix them with ammonia or vinegar. Read the labels of products in your home and following instructions for proper use. Many containers will state the most common dangers from interaction with other products.