Science, Tech, Math › Science Titrant Definition in Chemistry Share Flipboard Email Print Corbis via Getty Images / Getty Images Science Chemistry Chemical Laws Basics Molecules Periodic Table Projects & Experiments Scientific Method Biochemistry Physical Chemistry Medical Chemistry Chemistry In Everyday Life Famous Chemists Activities for Kids Abbreviations & Acronyms Biology Physics Geology Astronomy Weather & Climate By Anne Marie Helmenstine, Ph.D. Chemistry Expert Ph.D., Biomedical Sciences, University of Tennessee at Knoxville B.A., Physics and Mathematics, Hastings College Dr. Helmenstine holds a Ph.D. in biomedical sciences and is a science writer, educator, and consultant. She has taught science courses at the high school, college, and graduate levels. our editorial process Facebook Facebook Twitter Twitter Anne Marie Helmenstine, Ph.D. Updated November 30, 2018 In analytical chemistry, the titrant is a solution of known concentration that is added (titrated) to another solution to determine the concentration of a second chemical species. The titrant may also be called the titrator, the reagent, or the standard solution. In contrast, the analyte, or titrand, is the species of interest during a titration. When a known concentration and volume of titrant is reacted with the analyte, it's possible to determine the analyte concentration. How It Works The mole ratio between the reactants and products in a chemical equation is the key to using titration to determine an unknown concentration of a solution. Typically, a flask or beaker containing a precisely known volume of analyte, together with an indicator, is placed under a calibrated burette or pipette. The burette or pipette contains the titrant, which is added dropwise until the indicator shows a color change, indicating the titration endpoint. Color change indicators are tricky, because the color may temporarily change before permanently changing. This introduces some degree of error into the calculation. When the endpoint is reached, the volume of reactant is determined using the equation: Ca = CtVtM/Va Where Ca is the analyte concentration (usually given as molarity), Ct is titrant concentration (in the same units), Vt is the volume of titrant required to reach the endpoint (usually in liters), M is the mole ratio between the analyte and reactant from the balanced equation, and Va is the analyte volume (usually in liters).