Science, Tech, Math › Science The Cell Nucleus Definition, Structure, and Function Share Flipboard Email Print KATERYNA KON/SCIENCE PHOTO LIBRARY / Getty Images Science Biology Cell Biology Basics Genetics Organisms Anatomy Physiology Botany Ecology Chemistry Physics Geology Astronomy Weather & Climate By Regina Bailey Regina Bailey Biology Expert B.A., Biology, Emory University A.S., Nursing, Chattahoochee Technical College Regina Bailey is a board-certified registered nurse, science writer and educator. Her work has been featured in "Kaplan AP Biology" and "The Internet for Cellular and Molecular Biologists." Learn about our Editorial Process Updated on November 06, 2019 The cell nucleus is a membrane-bound structure that contains a cell's hereditary information and controls its growth and reproduction. It is the command center of a eukaryotic cell and is usually the most notable cell organelle in both size and function. Function The key function of the nucleus is to control cell growth and multiplication. This involves regulating gene expression, initiating cellular reproduction, and storing genetic material necessary for all of these tasks. In order for a nucleus to carry out important reproductive roles and other cell activities, it needs proteins and ribosomes. Protein and Ribosome Synthesis The nucleus regulates the synthesis of proteins in the cytoplasm through the use of messenger RNA (mRNA). Messenger RNA is a transcribed DNA segment that serves as a template for protein production. It is produced in the nucleus and travels to the cytoplasm through the nuclear pores of the nuclear envelope, which you'll read about below. Once in the cytoplasm, ribosomes and another RNA molecule called transfer RNA work together to translate mRNA in order to produce proteins. Physical Characteristics The shape of a nucleus varies from cell to cell but is often depicted as spherical. To understand more about the role of the nucleus, read about the structure and function of each of its parts. Nuclear Envelope and Nuclear Pores The cell nucleus is bound by a double membrane called the nuclear envelope. This membrane separates the contents of the nucleus from the cytoplasm, the gel-like substance containing all other organelles. The nuclear envelope consists of phospholipids that form a lipid bilayer much like that of the cell membrane. This lipid bilayer has nuclear pores that allow substances to enter and exit the nucleus, or transfer from the cytoplasm to the nucleoplasm. The nuclear envelope helps to maintain the shape of the nucleus. It is connected to the endoplasmic reticulum (ER) in such a way that the internal chamber of the nuclear envelope is continuous with the lumen, or inside, of the ER. This also allows the transfer of materials as well. Chromatin The nucleus houses chromosomes containing DNA. DNA holds heredity information and instructions for cell growth, development, and reproduction. When a cell is "resting", or not dividing, its chromosomes are organized into long entangled structures called chromatin. Nucleoplasm Nucleoplasm is the gelatinous substance within the nuclear envelope. Also called karyoplasm, this semi-aqueous material is similar to cytoplasm in that it is composed mainly of water with dissolved salts, enzymes, and organic molecules suspended within. The nucleolus and chromosomes are surrounded by nucleoplasm, which cushions and protects nuclear contents. Like the nuclear envelope, the nucleoplasm supports the nucleus to hold its shape. It also provides a medium by which materials, such as enzymes and nucleotides (DNA and RNA subunits), can be transported throughout the nucleus to its various parts. Nucleolus Contained within the nucleus is a dense, membrane-less structure composed of RNA and proteins called the nucleolus. The nucleolus contains nucleolar organizers, the parts of chromosomes carrying the genes for ribosome synthesis. The nucleolus helps to synthesize ribosomes by transcribing and assembling ribosomal RNA subunits. These subunits join together to form ribosomes during protein synthesis. Cite this Article Format mla apa chicago Your Citation Bailey, Regina. "The Cell Nucleus." ThoughtCo, Aug. 28, 2020, thoughtco.com/the-cell-nucleus-373362. Bailey, Regina. (2020, August 28). The Cell Nucleus. Retrieved from https://www.thoughtco.com/the-cell-nucleus-373362 Bailey, Regina. "The Cell Nucleus." ThoughtCo. https://www.thoughtco.com/the-cell-nucleus-373362 (accessed February 7, 2023). copy citation Watch Now: What Is a Chromosome?