Science, Tech, Math › Science What Is a Mole in Chemistry? Mole— A Unit of Measurement Share Flipboard Email Print ThoughtCo. Science Chemistry Basics Chemical Laws Molecules Periodic Table Projects & Experiments Scientific Method Biochemistry Physical Chemistry Medical Chemistry Chemistry In Everyday Life Famous Chemists Activities for Kids Abbreviations & Acronyms Biology Physics Geology Astronomy Weather & Climate By Anne Marie Helmenstine, Ph.D. Chemistry Expert Ph.D., Biomedical Sciences, University of Tennessee at Knoxville B.A., Physics and Mathematics, Hastings College Dr. Helmenstine holds a Ph.D. in biomedical sciences and is a science writer, educator, and consultant. She has taught science courses at the high school, college, and graduate levels. our editorial process Facebook Facebook Twitter Twitter Anne Marie Helmenstine, Ph.D. Updated May 06, 2019 A mole is simply a unit of measurement. Units are invented when existing units are inadequate. Chemical reactions often take place at levels where using grams wouldn't make sense, yet using absolute numbers of atoms/molecules/ions would be confusing, too. Like all units, a mole has to be based on something reproducible. A mole is the quantity of anything that has the same number of particles found in 12.000 grams of carbon-12. That number of particles is Avogadro's Number, which is roughly 6.02x1023. A mole of carbon atoms is 6.02x1023 carbon atoms. A mole of chemistry teachers is 6.02x1023 chemistry teachers. It's a lot easier to write the word 'mole' than to write '6.02x1023' anytime you want to refer to a large number of things. Basically, that's why this particular unit was invented. Why don't we simply stick with units like grams (and nanograms and kilograms, etc.)? The answer is that moles give us a consistent method to convert between atoms/molecules and grams. It's simply a convenient unit to use when performing calculations. You may not find it too convenient when you are first learning how to use it, but once you become familiar with it, a mole will be as normal a unit as, say, a dozen or a byte. Converting Moles To Grams One of the most common chemistry calculations is converting moles of a substance into grams. When you balance equations, you'll use the mole ratio between reactants and reagents. To do this conversion, all you need is a periodic table or another list of atomic masses. Example: How many grams of carbon dioxide is 0.2 moles of CO2? Look up the atomic masses of carbon and oxygen. This is the number of grams per one mole of atoms. Carbon (C) has 12.01 grams per mole.Oxygen (O) has 16.00 grams per mole. One molecule of carbon dioxide contains 1 carbon atom and 2 oxygen atoms, so: number of grams per mole CO2 = 12.01 + [2 x 16.00]number of grams per mole CO2 = 12.01 + 32.00number of grams per mole CO2 = 44.01 gram/mole Simply multiply this number of grams per mole times the number of moles you have in order to get the final answer: grams in 0.2 moles of CO2 = 0.2 moles x 44.01 grams/molegrams in 0.2 moles of CO2 = 8.80 grams It's good practice to make certain units cancel out to give you the one you need. In this case, the moles canceled out of the calculation, leaving you with grams. You can also convert grams to moles. View Article Sources "Avogadro constant." Fundamental Physical Constants, National Institute of Standards and Technology (NIST).